| Actor/Actress |
Role |
| Ray Romano |
Manny (voice) |
| John Leguizamo |
Sid (voice) |
| Denis Leary |
Diego (voice) |
| Queen Latifah |
Ellie (voice) |
| Simon Pegg |
Buck (voice) |
| Seann William Scott |
Crash (voice) |
| Karen Disher |
Scratte (voice) |
| Chris Wedge |
Scrat (voice) |
| Kristen Wiig |
Pudgy Beaver Mom (voice) |
| Eunice Cho |
Madison (Diatryma Girl) (voice) |
| Harrison Fahn |
Glypto Boy (voice) |
| Maile Flanagan |
Aardvark Mom (voice) |
| Jason Fricchione |
Adult Molehog Male (voice) |
| Bill Hader |
Gazelle (voice) |
| Kelly Keaton |
Molehog Mom / Shovelmouth Mom (voice) |
| Joey King |
Beaver Girl (voice) |
| Lucas Leguizamo |
Aardvark Boy / Beaver Kid #2 (voice) |
| Jane Lynch |
Diatryma Mom (voice) |
| Regan Mizrahi |
additional voices (adr loop group) |
| Clea Lewis |
Start Mom (voice) |
| Allegra Leguizamo |
Aardvark Girl (voice) / Additional Voices (voice) |
| Josh Peck |
Eddie (voice) |
| Carlos Saldanha |
Dinosaur Babies / Flightless Bird (voice) |
| Claudia Besso |
Additional Voice (voice) |
| Beatrice Miller |
Additional Voice (voice) |
| Christian Pikes |
Little Johnny (Aardvark Kid) (voice) |
| Avery Christopher Plum |
Beaver Kid #1 (voice) |
| Joe Romano |
Ronald (Shovelmouth Boy) (voice) |
| Manoela Scarpa Saldanha |
Molehog Girl 1 (voice) |
| Sofia Scarpa Saldanha |
Molehog Girl 2 (voice) |
| Cindy Slattery |
Bird (voice) |
| Matt Adler |
Additional Voice (voice) |
| Steve Alterman |
Additional Voice (voice) |
| Anthony Amorim |
Additional Voice (voice) |
| Holly Dorff |
Additional Voice (voice) |
| Nicole Ehinger |
Additional Voice (voice) |
| David H. Kramer |
Additional Voice (voice) |
| Selenis Leyva |
Additional Voice (voice) |
| Matt McCarthy |
Additional Voice (voice) |
| David McCharen |
Additional Voice (voice) |
| Tim Nordquist |
Additional Voice (voice) |
| Devika Parikh |
Additional Voice (voice) |
| Alexandra Pisacane |
Additional Voice (voice) |
| Jake Schwencke |
Additional Voice (voice) |
| Amanda Scott |
Additional Voice (voice) |
| Johnathan Tchaikovsky |
Additional Voice (voice) |
| Pamala Tyson |
Additional Voice (voice) |
| June Christopher |
Additional Voice (voice) |
| Beatrice Miller |
(voice) |
